Semaglutide
Common Side Effects: Nausea, vomiting, diarrhea, constipation, stomach pain, headacheSerious Adverse Events:
- Pancreatitis (severe abdominal pain radiating to back)
- Thyroid tumors/cancer (neck lumps, hoarseness, difficulty swallowing)
- Kidney problems/failure
- Severe allergic reactions (swelling, difficulty breathing)
- Gallbladder disease
- Diabetic retinopathy complications
- Severe hypoglycemia when combined with insulin/sulfonylureas
Tirzepatide
Common Side Effects: Nausea, vomiting, diarrhea, decreased appetite, constipation, indigestionSerious Adverse Events:
- Acute pancreatitis
- Medullary thyroid carcinoma
- Acute kidney injury
- Severe gastrointestinal disease
- Hypoglycemia (especially with other diabetes medications)
- Gallbladder disorders including cholecystitis
- Severe allergic reactions
Tadalafil
Common Side Effects: Headache, muscle aches, back pain, nasal congestion, flushingSerious Adverse Events:
- Priapism (painful erection >4 hours requiring emergency care)
- Sudden vision loss (NAION - non-arteritic anterior ischemic optic neuropathy)
- Sudden hearing loss or tinnitus
- Heart attack, stroke, irregular heartbeat
- Severe hypotension especially when combined with nitrates
- Severe allergic reactions
Sildenafil
Common Side Effects: Headache, flushing, nasal congestion, dizziness, upset stomachSerious Adverse Events:
- Priapism requiring immediate medical attention
- Sudden vision loss (NAION)
- Sudden decrease or loss of hearing
- Heart attack, sudden cardiac death
- Stroke
- Severe hypotension
- Pulmonary edema
Testosterone Injections
Common Side Effects: Injection site reactions, mood changes, acne, sleep apnea worseningSerious Adverse Events:
- Venous thromboembolism (blood clots in legs/lungs)
- Myocardial infarction and stroke
- Polycythemia (increased red blood cells leading to clotting risk)
- Severe liver toxicity
- Prostate cancer progression
- Severe mood disorders, depression, suicidal ideation
- Sleep apnea exacerbation
- Breast cancer (rare in men)
- Severe allergic reactions
Enclomiphene
Common Side Effects: Hot flashes, mood changes, headache, nauseaSerious Adverse Events:
- Visual disturbances (blurred vision, spots, flashes)
- Ovarian hyperstimulation-like syndrome
- Severe mood disorders, depression
- Liver dysfunction
- Deep vein thrombosis
- Severe allergic reactions
- Testicular tumors (rare)
Anastrozole
Common Side Effects: Joint pain, hot flashes, weakness, mood changesSerious Adverse Events:
- Severe bone loss/osteoporosis leading to fractures
- Cardiovascular events (heart attack, stroke)
- Severe depression, suicidal thoughts
- Liver dysfunction
- Severe allergic reactions including anaphylaxis
- Skin reactions (Stevens-Johnson syndrome)
- Severe joint pain and stiffness
NAD+ Injection
Common Side Effects: Injection site reactions, mild nausea, flushingSerious Adverse Events:
- Severe allergic reactions
- Injection site infections/abscesses
- Systemic infections from contaminated products
- Cardiovascular effects (limited data on long-term safety)
- Unknown long-term effects due to limited clinical data
B12 Injection
Common Side Effects: Injection site pain, mild diarrhea, anxiety, headacheSerious Adverse Events:
- Severe allergic reactions/anaphylaxis
- Hypokalemia (low potassium) - can be life-threatening
- Pulmonary edema
- Heart failure (rare)
- Blood clots
- Injection site infections
Glutathione Injection
Common Side Effects: Injection site reactions, skin lightening (with high doses)Serious Adverse Events:
- Severe allergic reactions
- Stevens-Johnson syndrome/toxic epidermal necrolysis
- Kidney dysfunction
- Liver toxicity
- Zinc deficiency
- Asthma exacerbation
- Infection from non-sterile injections
- Limited safety data - unknown long-term effects
Naltrexone (LDN)
Common Side Effects: Sleep disturbances, vivid dreams, headache, nausea, fatigueSerious Adverse Events:
- Hepatotoxicity (liver damage/failure) - especially at higher doses
- Severe depression, suicidal ideation
- Precipitated opioid withdrawal (if opioids in system)
- Severe allergic reactions
- Pneumonia, eosinophilia (rare)
Sermorelin
Common Side Effects: Injection site reactions, headache, flushing, difficulty swallowingSerious Adverse Events:
- Severe allergic reactions/anaphylaxis
- Injection site infections
- Glucose intolerance/diabetes
- Hypothyroidism
- Carpal tunnel syndrome
- Joint pain and swelling
- Increased cancer risk (theoretical due to growth hormone effects)
- Sleep apnea worsening
Critical Safety Information:
- All injectable medications carry risk of infection, nerve damage, and blood vessel injury at injection sites
- Seek immediate medical attention for signs of allergic reaction: difficulty breathing, swelling of face/throat, severe rash
- Report any unusual symptoms to your healthcare provider immediately
- These medications may interact with other drugs - provide complete medication list to your provider
- Regular monitoring and follow-up care is essential for safe use
Disclaimer: This is not a complete list of all possible adverse events. Individual risk factors vary. Consult your healthcare provider for personalized risk assessment and monitoring recommendations.
